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Benzocaine was the first of many local anesthetics with similar chemical structures and led to the synthesis and introduction of a variety of compounds with more efficacy and less toxicity.
Increasing dose to 45 mg/day provides little more efficacy and substantially increases risk of side effects (70).
Towards this end developing and positioning known phytochemicals that bind and activate PPARγ with more efficacy and safety, while promoting health benefits has become an absolute necessity.
Future clinical research should focus on refining interventions and gathering more efficacy and effectiveness data on health outcomes of the pediatric patients treated with these interventions.
The identification of those receptors, which play a crucial role in fibrosis, was necessary, because receptor antagonists often show more efficacy and safety than ligand antagonist.
The synergistic effects of GUT-70 and bortezomib may offer more efficacy and flexibility to the treatment of MCL with bortezomib.
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Since CD40L + cells are involved in the pathological development of many auto-immune diseases, A25 conjugated drug targeting systems may be useful for developing therapies that are more efficacies and with less side effects.
It uses underlying issues in health care (such as the need for more efficacy, safety, and quality of care) that are major issues in all western countries [ 28].
Despite the differences between the goal of our study and Kralewski's goal, and the different national settings of the researches, the underlying issues in health care (such as the need for more efficacy, safety, and quality of care) are also relevant in health care elsewhere [ 3, 7, 8, 28].
In controlled clinical trials with chemotherapy of moderate or high emesis potential, combined treatment with aprepitant, 5HT3 receptor antagonists, and dexamethasone showed more efficacy than 5HT3 receptor antagonists and dexamethasone alone.
Antimalarial drugs are losing more and more efficacy against the deadliest agent, Plasmodium falciparum.
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CEO of Professional Science Editing for Scientists @ prosciediting.com