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While this finding suggests that currents greater than the typically used 2 mA may be more efficacious, the safety and tolerability of higher currents have not been assessed in stroke patients.
The aim of this chapter is to provide some guidelines and strategies rendering easier and more efficacious the decision on which compounds to prepare and which ones to reject.
Remarkably, both the weight change data and our observations of the mice show that the later the time of initiation, the more efficacious the MY-24 treatment was.
The more the distribution is shifted to the left, the more efficacious the intervention is relative to its competitors.
Furthermore, studies have demonstrated that the larger the heterogeneity, the more efficacious the outcomes are post-LVRS [ 22, 23].
The hypothesis that the duration, intensity and magnitude of the treatment influence the results has been partially confirmed by our results, enabling us to conclude that, the higher the intensity and magnitude, the more efficacious the treatment.
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In not one of those cases did the Court "questio[n], in the absence of a more efficacious sanction, the continued application of the [exclusionary] rule to suppress evidence from the State's case" in a criminal trial.
Such an arrangement is all the more efficacious as the extremities, which are particularly vulnerable, are involved.
Vigabatrin was found to be more efficacious in the treatment of the symptomatic and the idiopathic type of infantile spasm.
Although the loose combinations of AS+SMP was slightly (not significantly) more efficacious than the fixed one, the fixed regimen of AS+SMP is most promising since it permits reduction of the treatment duration to a maximum of 24 h.
Comparator studies in obese animal models, which are highly predictive of clinical outcomes, indicate that 5-HT6 ligands may have the potential to be more efficacious in the treatment of obesity than the current generation of anti-obesity drugs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com