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Cytisine and varenicline have a similar efficacy at α4β2*, α3β4*, and α7 rodent nAChRs, but cytisine is more efficacious at α6β2* nAChRs (Grady et al, 2010; Salminen et al, 2004).
Results indicate the agent was accepted and liked, and was significantly more efficacious at increasing physical activity (daily steps walked) than the control.
In tests with various human cancer xenograft models, capecitabine was more efficacious at wider dose ranges than either 5-FU or 5′-DFUR and was significantly less toxic to the intestinal tract than the others in monkeys.
This personalized, adaptive mechanical breath may prove more efficacious at treating and preventing ARDS than the current standard of care.
40 Moreover, O'Brien et al showed that rituximab was more efficacious at higher doses in CLL patients.
Colloidal agents are more efficacious at restoring plasma volume compared with crystalloids, per unit of fluid given [ 1, 17].
Similar(38)
90 In conclusion, diazepam is more efficacious as an anticonvulsive medication at older developmental ages and its anticonvulsant effect is correlated with neuronal [Cl−]i.
The single exception was one study that showed that etoricoxib at 90 mg per day was more efficacious than naproxen at 500 mg twice daily in patients with RA [ 6].
Thiamethoxam as the sole active ingredient was used, not a more efficacious commercial product, at seed treatment rates that were lower than recommended as per common agricultural practices.
On the HAD anxiety subscale, venlafaxine XR, 75 or 150 mg/day, was significantly more efficacious than placebo at all time points except weeks 1 (both dosages) and 2 (150-mg/day dosage only) and significantly more efficacious than buspirone at all time points except week 1.
Both porphyrins are water soluble, but MnTnHex-2-PyP(5+) is approximately 4 orders of magnitude more lipophilic than MnTE-2-PyP(5+), which should positively affect its ability to pass through biological membranes, making it more efficacious in vivo at lower doses.
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