Sentence examples for more efficacious agents from inspiring English sources

As these more efficacious agents allow patients to survive longer and to receive more lines of therapy, issues have arisen concerning the choice of the best schedule and the best sequence of treatments.

Perhaps, treating schizophrenia more aggressively with more efficacious agents [ 39] or combination therapy [ 40] could result in more patients reaching remission and reduce the economic burden on the healthcare system, but more research is clearly needed.

There is, therefore, a need for new and more efficacious agents, targeted not only at treatment, but also at prevention of the disease, its progression, and its associated complications.

This combined with our reported observations suggest the FAM33A_1 siRNA is a more efficacious agent with a reduced off-target potential relative to the FAM33A_2 siRNA and would be the siRNA of choice for any future applications.

Among subjects with LDL-C at their minimal acceptable goal, an elevated LDL-P would confer risk that may be reduced by adjustment of the statin dosage, change in statin from a less efficacious to more efficacious agent, or the addition of a further LDL-P lowering agent.

Together, we have defined the underlying mechanisms of OXPHOS-dependent apoptotic pathway utilized by multiple anticancer agents, which may be exploited for future anticancer strategies or development of more efficacious anticancer agents.

In view of the unmet clinical need for more efficacious haemostatic agents in such patients, clinical studies are now justified to confirm the observed favourable effects of PCC in the present preclinical model system.

Dual inhibition of COX-2 and 5-LOX constitutes a rational concept for the design of more efficacious anti-tumor agents with an improved safety profile.

Thus novel, safe and more efficacious anti-inflammatory agents are needed for OA.

Significant efforts have been spent in recent years on the quest for safer and more efficacious anti-platelet agents.

Mapping synthetic lethal relationships in human cancer cells will hopefully enable us to use old drugs more wisely and to discover new drugs that are safer, and more efficacious, than existing agents.