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Novel approaches to environmental disinfection, such as hydrogen peroxide vapor decontamination [ 21, 22] are being trialed, however this approach may be more efficacious against surface environmental organisms such as MRSA and VRE, and efficacy against Enterobacteriaceae, especially those with an established water source, have not been demonstrated to date.
This high molecular prodrug was also found to be more efficacious against S-180 xenografted tumor than equivalent amount of doxorubicin.
Glu-Pt showed 6-fold increase in the MTD and was more efficacious against mouse L1210 ascetic leukemia than oxaliplatin at equitoxic doses.
The results show that Gal-Pt was more efficacious against H460 than cisplatin, and had superior potency in HT29 cells compared to oxaliplatin under nontoxic dosage conditions.
Mucosal, as opposed to systemic vaccination is often more efficacious against mucosal pathogens due to their ability to induce secretory IgA [1], [2].
Recent clinical trials, [8], [9] as well as DoD-based analyses of influenza, influenza-like illnesses and pneumonia-related healthcare encounters, [6], [7] suggest that TIV is more efficacious against laboratory-confirmed influenza among civilians as well as among highly-immunized military service members.
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Design and development of safer and more efficacious vaccines against Japanese encephalitis virus (JEV) is a high-priority target in the world.
Considerable efforts are aiming at the development of novel, safer and more efficacious vaccines against tuberculosis [1] [4].
Considerable efforts are aiming at the development of novel, safer and more efficacious vaccines against tuberculosis [1], [2].
CA074Me has previously been shown to be a more efficacious inhibitor against cathepsins B and L than is E64d [ 35, 55].
Recent approaches toward more efficacious interventions against TB, including shortening the length of the chemotherapy, include host-directed therapy (HDT) (Kaufmann et al., 2014).
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