Similarly, conditioned media from obese adipocytes induced IGF-1R phosphorylation twofold more effectively than those from lean individuals (Fig. 7d).
We concluded therefore that the lean mice more effectively cleave TRAP, so that the obese mice, in effect, selectively over-express the monomeric form of the protein with low enzyme activity.
It's about lean manufacturing and using resources more effectively.
Clinical trial data have shown that β-blockers alone (12) or in combination with doxazosin (13) more effectively lower blood pressure in obese than in lean hypertensive individuals.
The reformer machine at the core of the workout is supposed to make for a long, lean body and help flatten the abs more effectively than stomach-toning activities like crunches and situps.
"A lot of them have leaned down, through cuts and savings during the recession, and now they operate a lot more effectively," he explained.
We look at companies at their earliest stage of development and we believe with our capital that through the approach of the lean process and customer discovery that we can get companies up the learning curve, up the value curve, more effectively than other approaches...
The aim is to produce a leaner, more efficient, more responsive organisation that can adapt to the changing needs of patients in the 21st century and deliver more care, more effectively where patients need it, close to home.
They respond more effectively to training.
"Really captivating imagery teaches us more effectively".
