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It was also felt that four twin turrets allowed for a better field of fire and a more effective sequence of salvoes.
Improving depressive symptoms prior to an intensive dietary intervention might be a more effective sequence of treatment delivery for weight loss outcomes in women with depression.
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Further understanding of how mTOR inhibition influences the differential activation of upregulation versus downregulation of Akt by the mTORC1/mTORC2 complex could lead to the identification of genetic mutations and polymorphisms, development of tailored mTOR inhibitors, and more effective sequencing strategies for mTOR therapy.
This capability means that synteny-based methods are far more effective than sequence similarity-based methods in identifying true-negatives, a necessity for studying gene loss and gene transposition.
High-throughput sequencing would be much more effective if the sequences of interest could be captured prior to sequencing.
The alteration of the PTS1 of catalase to a more effective serine lysine leucine (SKL) sequence repolarized mitochondria and reduced cellular hydrogen peroxide levels and the number of senescent cells in a population (Terlecky et al. 2006; Koepke et al. 2007).
However, if sequencing costs continue to decline, it will eventually become more effective to employ sequencing techniques using the population of interest to find trait-associated variants.
The aim of our study was to determine whether HRMA was more effective than gene sequencing in identifying patients who would not benefit from anti-EGFR treatment.
High-resolution melting analysis identified 8% more KRAS-MUT patients not responding to cetuximab-containing regimens, suggesting that HRMA may be more effective than direct sequencing in selecting patients for anti-EGFR antibodies.
Although densities needed for these approaches are not reached, we do show here that wild rat-based SNP discovery is potentially much more effective than shotgun sequencing different inbred strains.
In the drug combinations, the simultaneous administration of gemcitabine and topotecan produced the highest apoptotic index either in A549 (34.0±3.6%) or in Calu-6 cells (27.6±3.6%), while the sequence topotecan → gemcitabine was more effective than the reverse sequence (Table 1).
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