Dangerous going forward, he frequently looked an absolute liability when defending but Allardyce's painstaking work on his body positioning has, almost imperceptibly, turned him into one of this team's more effective markers.
Further refinement of this result may lead to more effective marker-based selection and an improved understanding of the host regulation of resistance to this important disease.
However, more effective markers for prediction of patients' outcomes are still needed.
Simultaneously, for identification of more effective markers or genes by association analysis, further research need to focus on selecting candidate genes regulating heat tolerance of tall fescue or developing a large amount of single nucleotide polymorphism for genotyping larger association population.
Between them, hsa-miR-183 was the most significative of CSII, which miRNAs combination for CSII (hsa-miR-494, hsa-miR-183 and hsa-miR-21) was significant and were a more effective risk marker compared to the single miRNAs.
In the present study, we analyzed several factors, such as the histological grade (HG), ER status, PgR status, Ki67 (proliferation marker) labeling index (LI), and expression of p27Kip1 (an anti-proliferation marker) in order to identify more effective predictive markers for pCR after NAC with trastuzumab.
The locus rs1643660 could be more effective for marker-assisted selection of lines resistant to SCN.
Therefore, ALDH1A3/GPX3 may be more effective as markers for proliferation and differentiation of gallbladder carcinoma than as tools for predicting overall survival.
Selection on functional mutations, i.e. direct markers, is more effective than indirect markers (i.e. LD and linkage equilibrium markers) [ 49].
