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The first concerned the use of drugs in more effective combinations.
There are likely to be even more effective combinations of drugs that may come through.
He identified new mechanisms by which cancer cells become resistant to drugs, by turning on new pathways that bypass the drug's effect work first reported in Nature Genetics in 2012 and is now collaborating with several industry partners and planning clinical trials to use this new knowledge to develop more effective combinations that can overcome and prevent such bypassing events.
Further studies are warranted to identify the optimal dose of bevacizumab, as well as more effective combinations of bevacizumab in HCC (Thomas et al, 2009).
This may be due to arising targeted strategies and more effective combinations with biologicals against growth factors like Cetuximab and Bevacizumab (Jonker et al, 2000; Goldberg et al, 2004; Hurwitz et al, 2004).
Potentially more effective combinations such as 5-FU, doxorubicin and methotrexate (FAMTX), etoposide, doxorubicin, cisplatin (EAP), ELF and ECF were studied with varying response rates (Klein, 1989; Preusser et al, 1989; Findlay et al, 1994; di Bartolomeo et al, 1995).
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One prediction of our study is that Sorafenib combined with immune system treatments will be a more effective combination strategy than Sorafenib combined with any other targeted drugs.
We conducted a phase II study of combined chemoradiotherapy to find a more effective combination of drugs and radiation than those previously reported for such patients.
"It's hard to imagine a more effective combination of poor reasoning and bad policy making.
Finally, in the setting of metastatic disease, less toxic and more effective combination chemotherapy are sought.
Neither Ben Youngs nor Toby Flood have been at the height of their game in the last three months and you would argue that Danny Care and Jonny Wilkinson would, at this moment, make a more effective combination.
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CEO of Professional Science Editing for Scientists @ prosciediting.com