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Exact(23)
Collectively, we demonstrated for the first time that the cross-talk of TLR2 and TLR9 triggered Th1 activation collaboratively and our findings provided valuable information about designing more effective adjuvant for cancer therapy.
These trials will be important in establishing a role for this agent in the adjuvant setting and will hopefully lead to the development of more effective adjuvant chemotherapy regimens in the future.
Both formulations had a mean size near 500 nm and a positive charge; however, Chi-C48/80 NP was a more effective adjuvant delivery system when compared with Chi/Alg-C48/80 NP or C48/80 alone.
This may help clinicians to identify patients belonging to high risk for more effective adjuvant therapy in addition to the standard treatment protocol.
Altogether, these data indicate that C3d3/IFA is a more effective adjuvant combination than alum in eliciting a rapid and sustained antibody response to PA and, in particular, neutralizing antibodies to domain-4 after a single immunization.
More effective adjuvant treatment should also be investigated for those patients with high ALDH1 expression.
Similar(37)
However, with the development of new and less reactogenic vaccine antigens, which take advantage of molecular recombinant technologies, comes the need for more effective adjuvants that will facilitate the induction of adaptive immune responses.
Therefore there is a great need to develop more effective adjuvants.
However, more effective systemic adjuvant therapies after RH are needed for patients with AdCa.
Therefore, to improve the survival of patients with AdCa after RH, more effective systemic adjuvant therapies are required.
Although RH is still acceptable for treatment of patients with AdCa, a more effective systemic adjuvant therapy is required.
Related(20)
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