Sentence examples for more dynamic domains from inspiring English sources

Engineering of polyplexes with more dynamic domains is an encouraging new direction in nonviral vector design.

The co-localization of HDAC6 and Tau-1 in the more dynamic domain of the axon suggest a role of both proteins in promoting the microtubules cytoskeleton characteristics necessary for axonal growth and transport.

It is clear that our structure of Parkin has to be devoid of catalytic activity, yet the fact that our tagged Parkin fragments (which lack Ubl-mediated autoinhibition) show (weak) catalytic activity, and the notion that large conformational changes are required for activity, indicates a much more dynamic interplay between Parkin domains.

Although both demonstrate large dependence on dimerization for mediating their functions, KD for N-terminal dimerization is significantly high suggesting more dynamic role of this domain.

This work domain is more dynamic than those previously studied under EID because there is a constant potential for the addition and removal of devices, as well as changing configurations, making it important to study the generalizability of the framework.

We also leaded our experiments on a more dynamic application from robotic vision domain [19].

In support of this mechanism, the isolated APC regulatory domain becomes more dynamic in the absence of calcium, particularly in the region of the amphipathic α-helix as demonstrated by nuclear Overhauser effect experiments [16].

Structural comparison of the inward facing PepTSt structure with the occluded conformation of PepTSo supports our previous model where we proposed the C-terminal domain is more dynamic, with helices H10 and H11 facilitating opening of the central peptide-binding site to the interior of the cell during transport.

These data suggest that the regulation and the formation of constitutive heterochromatin domains may be more dynamic than anticipated.

A mechanism was proposed in which the regulatory domain binds to the carrier domain in the absence of calcium, capping it in order to block substrate transport [16], however that mechanism does not explain why the bound calcium-free regulatory domain would be more dynamic.

However recent studies argue that the domain landscape is more dynamic than previously imagined and that genes can be differentially regulated during normal development and differentiation and in the progression of disease states like cancer by redefining their domain organization (Bell and Felsenfeld, 2000; Witcher and Emerson, 2009; Gomes and Espinosa, 2010).