Sentence examples for more drastic alterations from inspiring English sources
He had made six changes and suggested further, more drastic alterations will follow when he can start trading.
Shifting visitation patterns under climate and environmental change may have more drastic alterations to the economic well-being of the region under a longer planning horizon.
Furthermore, inhibition of Rac-1 activity occurred over an extended time and thus differed from rapid and more drastic alterations studied in other model systems.
Yeasts of the acapsular mutant (Cap 67) presented more drastic alterations when grown in the presence of 1 μg/ml (Figs. 3B-D) or 2.5 μg/ml (Figs. 3E-F) of subfraction F2.4.
This may be owing to the more drastic alteration of structures surrounding L265 expected from the insertion of three irrelevant amino acids in L265RPP as compared with the single amino-acid substitution in L265P, which may also explain the difference in degradation through the ubiquitin-proteasome pathway.
Yeasts treated with 2.5 μg/ml of subfraction F2.4 showed more-drastic alterations with irregular buds emerging from the lateral of the mother cells instead of from the usual terminal, complete loss of the normal cellular ovular shape, cell wall detachment (arrows), membranous structures (arrowheads) and extracted cytoplasm suggesting cell death (Figs. 2E-F).
But we need far more drastic change.
When months pass like that, as we all know they sometimes do, measures more drastic than alterations in facial hair may need to be taken to keep the passage of time from becoming too oppressive.
Interestingly, yeasts of the acapsular mutant C. neoformans Cap 67 showed more drastic ultrastructural alterations than the other strains.
Unlike some other manufacturers the changes are subtle, more refinements rather than drastic alterations.
Nevertheless, cellular aneuploidy is a known feature of over 5,000 sorts of tumour.Adding or subtracting whole chromosomes is a much more plausible way to get drastic alterations in cell behaviour than the mutation of individual bases, Dr Duesberg argues.
