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As predicted, mosaic neurons with simultaneous loss of cullin3 and overexpression of Kelch demonstrated more dramatic phenotype.
However, lin-44; egl-20 double mutants have a more dramatic phenotype than lin-44 single mutants, with an overextension index of +2.5.
In SD brm mutants show a more dramatic phenotype than in LD (Figure S2) and, therefore, other developmental key pathways might be affected preventing the flowering transition (Figure 7).
While neither insertion strain exhibited a more dramatic phenotype than the complete hfq deletion strain during growth at 37°C, the lag phase of Tnhfq2 during heat shock was more pronounced than the hfq knockout strain (Fig. 3B and Fig. 6D).
Data exist showing that stepwise Apc loss might also induce a more dramatic phenotype (Fischer et al, 2012).
In agreement with Stone et al. (1983) and Mukae et al. (2002), we observed a more dramatic phenotype in st14 DNaseII lo egg chambers.
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In contrast, more dramatic phenotypes were observed in transgenic plants carrying the SCW HvCesA cDNAs.
35S AtCTF7∆B plants exhibit similar, if not more dramatic phenotypes than 35S NTAP AtCTF7∆B plants, indicating that the NTAP is not responsible for the observed phenotypes.
This is likely to contribute to the more dramatic phenotypes (e.g. lethality) in the model as compared to our patient.
Using homologues of human disease genes would allow for the use of strains with more dramatic phenotypes, which is likely to facilitate observations and to increase student appreciation for C. elegans as a model system.
First, overexpression of dlk-1 causes more dramatic phenotypes than rpm-1 loss of function (lf), including uncoordinated movement and small body size (Nakata et al. 2005; Abrams et al. 2008).
More suggestions(15)
more elongated phenotype
more apparent phenotype
more mesenchymal phenotype
more extreme phenotype
more invasive phenotype
more pronounced phenotype
more aggressive phenotype
more subtle phenotype
more differentiated phenotype
more normal phenotype
more epithelioid phenotype
more dramatic music
more tumorigenic phenotype
more complex phenotype
more modest phenotype
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