Sentence examples for more dose levels from inspiring English sources

Flexible models, like the Hill- and the Mult model, are needed for S-shaped continuous data but these models demand more dose levels in order to describe the data.

The precision of MED estimation using MCP-Mod is also evaluated comparing the design options of more dose levels and smaller sample size per dose versus fewer dose levels and larger sample size per dose.

With even more parameter uncertainty, even more dose levels might be needed.

The validity of the selected candidate dose was subsequently confirmed in a controlled trial using two or more dose levels.

However, although not explored in the present investigation, the precision of the drug parameter will most likely increase with the addition of more dose levels.

When there are three or more dose levels, we apply the pool-adjacent-violators algorithm [ 24] to obtain the order-restricted posterior samples.

The ability to induce cellular responses at somewhat lower and hence more realistic dose levels under ALI conditions may provide biologically more meaningful data than those obtainable with the conventional submerged exposures.

Besides predicting adverse drug reactions, pharmaco-metabonomics also has the potential to determine more effective dose levels for each individual.

In the lung, which had the highest number of modulated biological processes (108 processes), only 6 processes were detected at two or more absorbed dose levels.

This can be compared to the liver, which had the lowest number of modulated biological processes (37 processes), where as many as 17 processes were detected at two or more absorbed dose levels.

We prefer an average of 10 patients or more per dose level in order for the calculation of the posterior probabilities of the hypotheses to be meaningful.