Taken together, these results suggest that the mammalian granzyme clusters constitute an evolutionary response to special immune challenges, and that the cytotoxic immune response in humans proceeds through more diverse cellular pathways than the corresponding response in birds.
In contrast, the oxygen requirements of prokaryotes possessing the futalosine pathway were more diverse, including aerobic (34.9%), anaerobic (27.3%), microaerophilic (12.8%), and facultatively aerobic (7.6%) organisms.
Hence, although non-canonical Wnt signalling has been firmly linked with Closure 1 in mice, it is possible that genes in this pathway play more diverse roles in human neural tube closure.
Almost all pathways (48/50) were transcriptionally more diverse in the chemotherapy resistant group, suggesting that the greater transcriptional diversity in these tumors is global and not restricted to certain pathways (slope of regression line = 0.917, 95% confidence interval 0.877 to 0.956).
Creating a pathway for a more diverse talent pool to enter the technology industry has given the Techtonic Group, a development services firm that operates an outsourced apprenticeship program aimed at closing skill and equity gaps in high-tech fields, $2 million in new funding.
Secondary metabolic pathway genes are more diverse in comparison with those involved in primary metabolism.
It is now generally recognized that 7TMR signaling is much more diverse and that receptors can activate signaling pathways selectively mediated by multiple signaling conformations [1], [2].
The downregulated KEGG dataset was much more diverse but most notably included enzymes and pathways linked to terpenoid biosynthesis (e.g., HMG Co-A reductase; Table 3).
As compared to the moss, the cytokinin signaling pathway has, however, become more diverse during the evolution of land plants.
Of the Argonaute protein subfamily members, Ago2, the anti-viral RNase H-type nuclease, is significantly more diverse among mosquito species than the miRNA pathway nuclease, Ago1.
