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Their simulations indicated that polymers with stiff and semi-flexible backbones tend to wrap around the SWNT with more distinct conformations than those with flexible backbones.
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Related to this point, it is easy to imagine that, in those situations, the INK4b-ARF-INK4a locus might assume a more distinct conformation than that described here.
This result suggests that, although the active-site lid can sample at least two distinct conformations, the closed form is presumably a more favourable, lower free-energy state.
As such chemical shift differences imply distinct conformations, we have referred to these Gln as conformers "a" and "b".
By use of Nrf2 mutants we found that the complex exists in two distinct conformations in the basal state, suggesting that the Keap1: Nrf2 complex is much more dynamic than previously anticipated.
But the parties are ideologically more distinct.
It could hardly be more distinct.
First, TG2 exists in two distinct conformations, referred to as closed and open conformations, respectively [4, 5].
Arrestins exist in at least three distinct conformations: free, receptor-bound, and microtubule-bound.
Interestingly, the ATRX and Rassf1c peptides adopt distinct conformations for DHBDAXX targeting.
Moreover, we show that nascent chains adopt distinct conformations within the ribosomal exit tunnel.
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