However, on the codon pair tree (RDCU tree), species are more distant from each other (codon pair usage is less similar).
We also tested the conservation of more distant (1 3, 1 4, 1 5) codon pairs.
This is likely due to the fact that 3rd codon positions, in comparisons among more distant sequences, are highly saturated, and therefore tend to blur the phylogenetic signal at deeper nodes, hence the decrease in posterior probabilities.
These observations again suggest that phylogenetic information contained in codon usage similarity values is better appropriated to classify more distant groups.
In contrast, transfers may be more likely for SpG8 genes shared with more distant genomic species such as G1 (SpG8-3 and SpG8-6a gene clusters) or G4 (Atu4215-4218 in cluster SpG8-6b), whave have sporadic-like codon usage signatures.
Little by little, he grew more distant.
Security is an even more distant prospect.
Now those goals seem even more distant.
She grew older, more distant and polite.
