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Thus, the arrows that connect more distant chromosomes in this order, show a proportional increased semi-circle radius (a radius proportional with the relative distance between them).
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Two other QTLs were detected in a Large White population [ 30], although at more distant chromosome positions.
We were able to analyze SALL3 and ATP9B genes and the genes more distant on chromosome 18 (MBP at the proximal side and NFATC1 at the distal side).
Members of the matrilin family were included in all blocks, and other gene families identified in our local searches were represented in individual paired blocks along with genes that are more distant on each chromosome.
Interestingly, centromeric or pericentromeric sites more distant from the lacOs on chromosome 4 did not show appreciable increases in either Scc1 or Scc2 levels upon Scc4-lacI production, and tethered Scc4-LacI recruited Scc2 more efficiently than Scc1.
However, experiments in mice in which the H region is deleted show that, while it is essential for transcription of nearby ORs, it appears dispensable for the transcription of more distant ORs and ORs on other chromosomes [ 34, 35].
Two chromosome 5 genes are more distant homologs, distinct from the human chitinases/chitolectins.
RAPGEF5 is also located on chromosome 7 but is more distant from EGFR, being at position 7p15.3.
When individuals in the reference population are more related, they will share longer stretches of chromosomes surrounding the QTL, allowing more distant markers to explain QTL variation within the reference population.
Fifty pairs were found to be present in neighboring genomic locations within one million base pairs, while the other 45 were present in more distant locations (> 1 Mb) on the same chromosomes.
The search continues as the window size is shrunk in each chromosome sweep in order to capture more distant relationships.
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