For the remaining genes more distant and sporadic associations have been mined in the literature for relevant diseases or other types of cancer, e.g. AMDHD1 and PHACTR1 have been linked to tobacco use disorders [ 28] or RPRM with colorectal cancers [ 29].
For more distant relatives, the association was smaller, but statistically significant.
Here, cis-eQTL represents the cases where the regulated genes are located within 1 Mb of the regulatory SNP, while trans-eQTL indicates associations for more distant eQTL.
As the Acc1 data set provides higher resolution, the association appears more distant, but it is clear that both F. arundinacea var.
We found significant associations for Manhattan on lag 0 and lag 3 and for the Bronx on lag 0. We found a positive association in Brooklyn for same-day exposures to this source but no such associations for the more distant boroughs, Staten Island and Queens.
On the other hand, associations between ED visits and exposures represented by the southwest monitor, which is more distant from the residences of interest, diverged with associations with the AERMOD estimates.
First, air pollution was associated with lower scores on reasoning, with stronger associations for the years more distant in time compared with the year of or year before the cognitive assessment.
More distant candidate genes for this 7p15.2 endometriosis association signal include HOXA10 (Homeobox A10) and HOXA11 (Homeobox A11) which are ∼1.35 Mb downstream.
DSWMH predominantly disrupts short association fibres that link adjacent gyri, while PVH affects long association fibres that connect the more distant cortical areas.
It has also been suggested that a more distant gene on 9p21, MTAP (Fig. 1), could mediate disease associations [3], [4].
