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Watts et al. (1987) more directly demonstrated that the EIP for DENV-2 virus in Ae. aegypti mosquitoes is temperature dependent by allowing infected mosquitoes to feed on monkeys.
Garzia et al (2009) also more directly demonstrated that miR-199b-5p miR-199b-5p miR-199b-5pthe cancer stem-cell poverexpression xenogreducesuse model, resultheg in impaired medulloblastoma tumour development.
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Other studies more directly demonstrate the pre-existence of an arrhythmogenic substrate in patients who do develop POAF.
To more directly demonstrate intact autophagic flux in SLE, isolated CD19+ B cells were incubated with chloroquine, an alternative lysosomal acidification inhibitor, and LC3 punctae measured by MIFC.
To more directly demonstrate that the population of cells forming hyperplasia arose from alveolar epithelium surviving involution after lactation, the WapInt6sh mouse was crossed with the WapCreRosa26stop mouse.
To more directly demonstrate the immunoregulatory effect of liver-primed CD8+ Treg cells on antigen-specific CD8+ Teff cell responses in vivo, day 7 Ad-Ova SC splenic CD8+ T cells, day 7 IV liver CD8+ Treg cells, and CFSE-labeled naïve Thy1.1+ CD8+ OT-I T cells were adoptively transferred into naïve Thy1.2 +/ + C57BL/6 mice.
However, the tasks performed during the daily activity study were unknown and the capacity of this method to distinguish more and less complex tasks has yet to be directly demonstrated.
Prions cannot be directly demonstrated in excreta or soil.
However, there are examples where benefits can be directly demonstrated.
A rather more scientific method for directly demonstrating accurate synchronisation consisted in the simultaneous capture of a fast moving object against a reference background.
Here, we explore the nature of the protein-protein connectivities more directly and conclusively demonstrate that PPI networks indeed contain degree-weighted elements.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com