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"I've gone through a number of start-up companies," said Mr. McAdam, "and this has been more difficult than previously".
But it appears more difficult than previously believed for private industry to raise the billions of dollars needed to build and operate a shuttle replacement, Ms. Dasch said.
This suggests that adaptation to climatic change may be more difficult than previously believed, and that the accumulation of wealth, technology and experience might not substantially mitigate global economic losses during this century.
"In the post-9/11 world, we've found it has, until very recently anyway, been more difficult than previously to get the common reader to take a chance on new writers," said Jonathan Galassi, the president and publisher of Farrar, Straus & Giroux, which publishes Jonathan Franzen and Nadine Gordimer, as well as Marilynne Robinson.
"Clearly doing business in some emerging markets is proving to be more difficult than previously expected," said Michael Kovacocy, an analyst with Daiwa Institute of Research, who rated the stock "sell".
Both seem more difficult than previously assumed as the necessity of providing available and missing evidence is required to bring about the integration of translational molecular biological data to clinical processes such as the cancer classifications proposed by the American Joint Cancer Committee AJCCC).
Similar(46)
One of his central goals, going all the way back to his 2004 convention speech, of building common ground between Americans of different ideologies and backgrounds is going to be more difficult than was previously anticipated.
The construction of a three dimensional ARc is far more difficult than the previously described process for two dimensions.
The discovery is worrying because it indicates that the species' fight to survive may be even more difficult than had been previously thought.
But some of the puzzles are more difficult than any I've previously encountered in the series.
The prime minister also said she preferred Christmas shopping in person rather than online, noting that this year the process was "going to be more difficult than it has been previously".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com