Sentence examples for more difficult necessitating from inspiring English sources
This lack of prior exposure makes the population more vulnerable to severe disease caused by highly virulent H5N1 strains and makes immunization more difficult, necessitating the use of adjuvants, higher antigen content, and two doses to elicit sufficient antibody titers (7).
The latter is more difficult to establish, necessitating the development of specialised statistical methods.
Rarer instances are obviously much more difficult to find and necessitate gathering enormously larger amounts of data.
The work of delirium prevention as a meaningful set of practices posed even more difficult challenges for staff, since prevention necessitates a more complex understanding of a problem than how to manage it.
Furthermore, the immature immune system may necessitate repeated vaccination, making it more difficult to reach protective immunity during the vulnerable early months after birth.
His tall and thin dialogue balloons necessitated frequent hyphenation, which made the dialogue more difficult to read.
This may necessitate multiple spray rounds which can make it more difficult to achieve and maintain high spray coverage.
After an initial flush of enthusiasm, the task of abandoning the centralized planning system proved to be far more difficult than anticipated, in part because the magnitude of such a change would have necessitated the creation of a new structure of economic (managerial) power, independent of, and to some extent in continuous tension with, that of political power, much as under capitalism.
Moreover, the actual PDT treatment approach necessitates being able to get the light to the tumour, which is more difficult for orthotopic tumours.
