More difficult than experimenting with new treatment approaches, members of the group say, is stripping away the stigma that still shrouds much discussion of H.I.V. among blacks in the South.
A major problem with research on ageing in humans is that it is much more difficult to do experiments, both for obvious ethical reasons and the long experimental time required, and thus shorter-lived models are usually preferred.
The downside of this approach could be increased deviation of results obtained with similar strains in other laboratories due to increased genetic drift, which may make it more difficult to reproduce experiments at another location.
Considering how difficult it can be to experimentally test hypotheses that result in definitive answers about an animal's behavior based on its vision, hearing, touch, taste, or smell, it becomes far more difficult to design experiments that give clear answers involving a combination of these perceptual modalities.
Identification of toxic oligomeric species is, however, more difficult and FCS experiments in which mobile Q35 was monitored in C. elegans cell lysates, or after being purified from C. elegans revealed a heterogeneous oligomeric population where the population shifted to slower moving species as the animals aged.
It is possible that as our lesions were shorter than in real cases, their identification was more difficult in our experiment compared to naturally occurring injuries.
"It makes experiments more difficult as well as more lengthy," he says.
However, attempts to adapt the virus to cell culture have so far been unsuccessful [65], making these experiments more difficult.
However, the resulting epifluorescence illumination geometry results in lower excitation intensities, higher background, and increased photodamage rendering live-cell super-resolution imaging experiments more difficult.
Although the eat-2 mutation is not a null mutation, which renders the interpretation of these experiments more difficult, these findings also suggest that eat-2 and sDR evoke mostly independent, though overlapping, pathways to extend lifespan.
