We also chose some more difficult examples, for which the closest available reference was much more distant, for example, in a different taxonomic order in the case of the bird.
Although the concepts addressed in learning goal 1 are interwoven through both courses, the majors use more difficult examples and extend these concepts more in homework assignments and exam questions as the course progresses, because their course material is unquestionably more detailed (Supplemental Material A and B).
In a more difficult case, for example where the positive proportion was very close to the high prevalence threshold (0.149), the sequential strategy still performed very well, returning a classification of moderate prevalence on ~23% of occasions, of high prevalence on ~77% and of low prevalence almost never.
The aim of the weak learner is to find a good weak hypothesis h t : X → {-1, +1} for the distribution D t, where goodness is measured by the error of the hypothesis with respect to D t. Then D t is updated such that incorrectly classified examples have their weights increased, forcing the weak classifier to concentrate on the more difficult training examples.
Although great strides have been made in extracting this information, ranging from the simple, for example, identification of protein-coding regions, to the more difficult, for example, identification of regulatory elements (Hughes et al. 2000; Wasserman and Sandelin 2004; Dunham et al. 2012; Kundaje et al. 2015), much of this information remains untapped.
"We studied all the issues of Zaatari, compared, and tried to avoid them this time," says a Jordanian security man at Azraq.Smuggling will be more difficult, for example, because Azraq sits fenced in an inhospitable desert surrounded by watchtowers.
Nailing down exactly how many stadiums they have played in is rather more difficult – for example, Madrid has hosted 61 Spain games at six grounds, with the Bernabéu, Vicente Calderón, and the Coliseum Alfonso Pérez in Getafe hosting matches as well as Real's old grounds Estadio de Chamartín and Campo de O'Donnell and Atléti's old Estadio Metropolitano.
Companies are constructing ever bigger turbines, which should prove more economic in the long run despite their higher initial costs; and are moving into locations where construction is more difficult, for example in deeper water.
The characteristics of these narratives correspond in varying degree to the diagnostic criteria of DSM-IV [ 42], making it more difficult, for example, to recognize "Struck by lightning" as depression.
This will obviously influence the MRIs of that joint, often rendering their interpretation more difficult – for example, in defining the edge of the graft to assess the degree of overgrowth or incorporation.
Along with the limited number of studies targeting the elderly population, the low quality of the existing studies makes the interpretation of the evidence still more difficult; for example, only one third of the studies included in this review were of high quality.
