Sentence examples for more differentiated type from inspiring English sources

Fillmore C. and Kuperwasser C. supposed that CD24+ population was mainly characterized by less differentiated basal type of breast cancer, and CD44+ cells caused the development of luminal form of breast cancer, being more differentiated type of tumor [37].

It is interesting to observe that two types of redundancies have been observed in real cells, when moving in a signal-driven way from an intermediate type A to a more differentiated type B: in some cases the transition can be achieved by acting on different genes of A [38], and in other cases B may be reached also by acting on a cell type C which does not belong to the lineage of A [23][39].

Interestingly enough, this histological "conversion" into a more differentiated type at the metastatic location has been observed in a few series of patients with GCTs [ 6].

Slices of tumour cultured in the presence of testosterone showed a morphological change to a more differentiated type of neoplasm whereas explants cultured in the absence of steroid hormone, or with stilboestrol diphosphate, showed no change.

RGs, also known as Type 1 cells from the SGZ, express Nestin, Gfap and Blbp, whereas slightly more differentiated type 2/2a cells lose Gfap and Blbp expression (Steiner et al., 2006; Morrens et al., 2012).

This unidirectional state transition could for example model cell differentiation, where a progenitor transforms into a more differentiated cell type, but the reverse transition does not occur naturally.

In the present study we found lower CTIP2 expression in more differentiated tumor type and CTIP2 expression increased with loss of differentiation.

The objective of this long-term in vivo study was to investigate cellular differentiation and tissue formation of transplanted undifferentiated bone-marrow-derived mesenchymal progenitor cells (BMPCs) in combination with a medical grade polycaprolactone (mPCL) scaffold and to compare them to osteoblasts; a more differentiated cell type in a calvarial defect model.

It is not clear how many stem cells (that can give rise to a more differentiated cell type and self-renew) [35], as opposed to progenitor cells that cannot self-renew, there are within skeletal muscle.

However, the association of EBV with the more differentiated, WHO type I form of NPC has been found particularly in the geographical regions with a high incidence of undifferentiated NPC [14].

Analysis of breast tissue from prepubertal rats injected with genistein revealed a decrease in the number of immature terminal end-buds, together with an increase in the more differentiated lobules type II [ 38].