Sentence examples for more differentiated expression from inspiring English sources

HaGAS and the HaCS showed a much more differentiated expression.

First, BAT is more 'brown', that is more differentiated, with higher expression of UCP1 that uncouples mitochondria, making them more 'leaky', expending more energy (Berniakovich et al., 2008), and multiple differentiation markers are elevated in ShcKO BAT.

Recent studies have supported this hypothesis since human synovial sarcoma cells displayed features of multipotent stem cells whose differentiation capacity was deregulated by the oncogene [ 3, 4], and transgenic mouse modeling revealed that tumors recapitulating SS features developed in precursors of the muscle lineage but not in more differentiated myocytes upon expression of the oncogene [ 5].

In the present study we found lower CTIP2 expression in more differentiated tumor type and CTIP2 expression increased with loss of differentiation.

hPaca1 has an undifferentiated phenotype similar to Panc1, with high ZEB1 and low E-cadherin, miR-200, and miR-203 expression, whereas hPaca2 is more differentiated with an inverse expression pattern, similar to BxPC3 (Supplementary Fig S2A).

Cells in which heterogeneous Nanog expression was initially induced showed a more differentiated morphology and an enhanced expression of differentiation markers in comparison to cells maintained in 1 μg/ml doxycycline.

We have shown that in the present cohort of NSCLC patients S100A4-positive tumors were smaller and more differentiated than tumors without expression.

Expression levels of S100A4 and ephrin-A1 were significantly higher in adenocarcinomas compared to other histological subtypes, and S100A4-positive tumors were smaller and more differentiated than tumors without expression.

In contrast with most carcinomas that lose epithelial characteristics with tumour progression, EOCs undergo a mesenchymal epithelial transition, acquire a more differentiated phenotype and gain expression of E-cadherin (reviewed in [ 11]).

Results from previous investigations utilizing the label-retaining assay suggest that the proximal region of the mouse prostate is more likely to contain adult prostate stem cells that express basal markers and that the distal region of the duct contains more differentiated luminal cells, with expression of luminal makers [ 11, 12].

We performed a shRNA mediated knockdown of Msi1 in Daoy and found that cancer cells expressing low levels of Msi1 were less clonogenic (proliferation assay), more differentiated (higher βIII Tubulin expression) and, possibly, more apoptotic (lower Bcl2 expression).