Sentence examples for more differentiated cellular from inspiring English sources

The results of the study support the notion that sequential activation of these two modifications specifies the transition from the "stem-like" neural precursor state to a more differentiated cellular state.

The involvement of type I and type II PRMTs is not always clear cut with respect to their roles in the maintenance of "stem-like" or the more differentiated cellular state.

Whether this interaction or any other interactions with NRs may result in a more differentiated cellular phenotype remains unclear.

As a consequence of this, CD44+ cells specifically respond to an inhibitor of TGFβR, and acquire more differentiated epithelial cellular morphology and membrane localization of E-cadherin and β-catenin.

Possibly, in some cell types the sequential activation of the two different PRMT subclasses may specify the progressive restriction of multipotency and a transition from a "stem-like" to a more differentiated and developmentally restricted cellular state.

In accordance with a crucial role in suppressing salivary gland tumor progression, WIF1 re-expression in salivary gland tumor cells inhibited cell proliferation, induced more differentiated phenotype and promoted cellular senescence, possibly through upregulation of tumor-suppressor genes, such as p53 and p21.

In addition, a redirection of the cellular machinery towards a more differentiated phenotype may occur.

Cancer stem cells exhibit distinctive cellular metabolism compared with the more differentiated counterparts or normal cells.

However, after HBO treatment a majority of the cases appeared to have a more differentiated morphology, with glandular structures and less marked cellular atypia as well as areas of cell death (n = 5) (Fig. 1C).

As Brk enhances the effects of signaling via Erb receptors [ 8, 9] suppression of Brk would be predicted to reduce the effects of Erb signaling, in which this cellular context results in a more differentiated phenotype.

Nuclear ADA3 expression was associated with more differentiated tumors (grade 1 and 2), lower degree of cellular pleomorphism (p ≤ 0.001), low proliferation status, the absence of vascular invasion (p = 0.008), and excellent to good NPI.