Melanocyte development provides an excellent model for studying more complex developmental processes.
More specifically, developmental processes are highly regulated by the appearance and disappearance of particular transcription factors [ 5, 7- 9].
Studies in the 2015 Collection, as in years past, evaluated biomarkers in pregnant women and children, not only in the context of identifying avenues for early-life exposures, but also for characterizing molecular initiating events operating on one or more critical developmental processes in the pathway toward disease.
Many of the toxic agents known to damage the developing brain interfere with one or more of these developmental processes.
Developmental exposure of animals or humans to numerous agents (e.g., X-ray irradiation, methylazoxymethanol, ethanol, lead, methyl mercury, or chlorpyrifos) demonstrates that interference with one or more of these developmental processes can lead to developmental neurotoxicity.
With the explosive increase in nucleotide sequence information in EST databases and new technologies such as microarray analysis, it should now be possible to delve more deeply into developmental processes of tomato fruit ripening.
These cycles are presumably necessary to replace F-box proteins which had been ubiquitinated due to the lack of substrates, or to replace F-box proteins which are no more required during developmental processes (Braus et al. 2010).
Nursing behavior, occurring during very early adult life, may involve more diverse physiological and developmental processes, and nursing itself may also involve more diverse behaviors and physiological processes, such as food processing and the synthesis of glandular secretions that are fed to larvae.
The highlighted developmental principles likely apply more generally to other developmental processes, including neurogenesis and angiogenesis.
It was anticipated that this would reveal additional 'molecularly-defined' compartments more representative of key developmental processes, including segmentation and patterning, and possibly also identify specific cell types within complex and heterogeneous compartments.
