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We propose that each light chain exhibits one or more determinants of organ-specificity, which originate from primary structure and post-translational modifications.
We conclude that although the use of a specific gene influences the tissue distribution of amyloid, each light chain exhibits one or more determinants of organ-specificity, which originate from somatic mutations and post-translational modifications.
We have studied many more determinants of the response rate to PROM questionnaires mailed to patients after a hospital episode than have been considered previously in published studies.
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Economic factors are proven to be at least equal to if not more determinant of the occurrence of invasive species than climatic factors.
Thus, it is likely that the functional architecture of the cortex is more determinant of the neuronal synchronization dynamics than previously thought.
I suggested that by creating dubious concoctions of refined wheat, sugar, salt, and the worst varieties of fat, they were creating a demand for ever more of the same- since familiarity is among the more potent determinants of taste preference.
It is more likely that the severity of physiological derangement and organ dysfunction, as in our findings, are more important determinants of outcome.
It is uncomfortable to realise that what John Locke called the "law of the club" – actual social attitudes found in people to whom one listens – could be more powerful determinants of behaviour than the directives of morality.
Ratio and group size may be more important determinants of quality for infants and toddlers than for older children.
For example, the "Haddon matrix" emphasizes more proximal determinants of road injuries without assuming that national income is required to alter these determinants.
These findings suggest that self-efficacy beliefs are more important determinants of disability than fear avoidance beliefs in primary health care patients with musculoskeletal pain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com