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Using a Monte Carlo method: A more robust, but more demanding, confidence limit calculation uses Monte Carlo methods.
However, setting up the T matrix is computationally more demanding than the calculation of its inverse with the algorithm proposed in this study.
The explicit inclusion of exact-exchange Hartree-Fock terms make these calculations computationally much more demanding compared to the earlier GGA calculations, and hybrid functional calculations have become routine only in recent years.
Although its calculation is computationally much more demanding than are many of the other calculations in similarity cheminformatics [46, 53 65] (and see below), this essential independence from both the encoding and the similarity metric means that it is a principled strategy that we considered worth exploring for the drug metabolite similarity problem.
Switching on non-hydrostatic dynamics — ordinarily ignored by ocean modelers — made the calculations much more demanding, but revealed new features, such as internal gravity waves, which are not properly resolved by hydrostatic models.
We also note that Reporter GSEA was computationally much more demanding as opposed to Reporter Features calculation (Additional file 8).
Students have become more demanding and jobs more in demand.
The iterative procedure for the nonlinear equation (21) is even more demanding than in the cases of robust STFT and robust WD calculations [6, 11].
Accordingly we could not base our calculations of incidence proportions on those free of pain at baseline, but had to use the more demanding criterion of study participants being free from pain during the entire preceding year.
Men are much more demanding".
Mom is the more demanding diner.
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