We have more definitively identified M. abscessus strains in potable water, as strains that are indistinguishable from those found in samples from patients known to have disease.
While these are sufficient to document unit costs and their variations, they are insufficient to support a robust multivariate analytic approach that might more definitively identifies the correlates of efficiency.
Double-stranded DNA breaks were more definitively identified by co-labelling for phospho-H2AX and proteins that respond to DNA damage, i.e. either promyelocytic leukaemia protein (PML; H-238 (1 100), Santa Cruz, Dallas, TX, USA) or Rad51 (H-92 (1 100), Santa Cruz, Dallas, TX, USA).
In order to more quickly and definitively identify ceramide species in tissues, we incorporated an on-tissue digestion of ceramides in kidney tissues with recombinant bacterial ceramidase from Pseudomonas aeroginosa (bCDase) prior to MALDI-IMS.
It is possible that a larger sample size and more rigorously performed studies would definitively identify an important benefit in the total patient population, or in a subgroup.
Instead, a more robust statistical approach, such as HLM, is required to definitively identify gender performance differences.
However, further study with more patients is needed to determine the efficacy of novel agent combined chemotherapy and to definitively identify the prognostic factors.
It passed through the officer's torso, but investigators could never definitively identify the death slug.
The all-white jury in the trial never heard the victim definitively identify her attacker.
A match would have helped to definitively identify the extremist leader.
