The more critical a functional region is, the greater the purifying selection to maintain it and the greater the signature of sequence conservation we expect to see.
Is the stronger diversity-productivity relationship in naturally assembled communities driven more by critical functional traits, or would PD still better explain productivity?
These studies, with functional group modified PALA derivatives, showed that amide groups can be a useful substitute of the carboxylate in order to reduce the charge on the molecule, and indicate that the relative position of the functional group in the β-position is more critical than the nature of the functional group.
In addition, the instillation of MCP-1-neutralizing antibodies into mouse lungs blocks cytokine secretion and induces more severe pneumonia, indicating a critical functional role of this particular chemokine.
Rigorous normalisation of miRNA data may be more critical than that of other RNA functional classes [ 18].
Further, in some systems or under some environmental conditions the critical functional traits may have much more important roles and thus more explanatory value than PD.
This is because Japanese exports of high-tech commodities might be of higher quality (e.g., low energy consumption, low noise, high durability, multi-functional) and might require more critical metals than the same commodities produced in developing countries.
Given the shift toward reimbursing for positive health outcomes rather than fee for service, it is even more critical to design tailored solutions that target both functional and emotional needs to help this group live long, healthy and happy lives.
As it stands, our data suggest there is a functional hierarchy of CST subunit function in budding yeast with Ten1 more critical than Stn1, which is more critical than Cdc13.
Others were more critical.
