Some authors emphasize the importance of quality (higher accuracy amounts to more correct predictions) over quantity (a higher number of predictions), we used ROCR package in R language environment to accomplish this computation [53] and gave out a proper logL threshold for both of the two metrics (e.g. FPR and sensitivity).
It is interesting to note that several biopathways, such as 'Cell cycle - yeast', 'Ribosome biogenesis in Eukaryotes' and 'Meiosis - yeast' which are specific to yeast cell cycle, have more correct predictions of gene interactions and were ranked 2nd, 3rd and 5th, respectively, in Table 2 according to the number of the correct predictions.
We identify examples where LCA made an overly conservative prediction, but SPANNER produced a more precise and correct prediction.
This is because if one gene is in 100 GO categories (high multifunctionality), and another is in only one (low multifunctionality), by placing the former gene ahead of the latter gene in a fixed ranking, we make a correct prediction more often across all GO categories.
Although a number of reporter genes are good CFS predictors in the training set, the majority perform no better than random, 32 of the 44 making more incorrect than correct predictions on the test set (Tables S3, S4).
In this process, errors are more informative than correct predictions.
As long as there are more correct classifiers than incorrect, then the prediction will be accurate.
Furthermore, reliable energy predictions lead to more correct economic analyses that can stimulate the diffusion of the PV technology.
Because with a better model the predictions will be more correct, a better model should in general lead to less units responding, which is also consistent with the interpretation that sharpening of responses can occur (Fritz et al., 2007; Scheich et al., 2007; Waszak et al., 2012).
