It is usually a good practice to start with a large range and big increment (e.g., 1 or 2) to perform an initial optimized deconvolution, to guide the selection of a more constrained ln u) range with finer increment.
This suggests that S. pombe is adapted for proliferating in a more constrained ecological range than the baker's yeasts.
While the large population was given artificially wide parameter ranges for the purpose of the sensitivity analysis, the small human sample population was constructed with more constrained parameter ranges for the purpose of approximating a plausible population of humans.
Because of the tight balance between oxygen risks in aquatic species with weaker respiratory control, they are likely to have more constrained, predictable ranges than terrestrial taxa which are inherently better able to regulate oxygen levels [ 17].
Whales and dolphins can cope with a wide range of temperatures but their fish and squid prey tend to be more constrained, and their ranges are extending significantly northwards".
Their range of alternatives may be constrained by wartime circumstance — more constrained than Cardona's.
The real situation could probably be more complex, as a duplicate that is not important for the function will tend to be less constrained (some proteins are more constrained than others; environmental proteins may have less constrained sites).
In contrast, the range of membrane properties should be more constrained, as presumably different frequencies correspond to membrane proteins that come from slightly different genes.
Given that there is a ceiling on how many responses are available, the range of scores on the recognition trials is more constrained than that on the recall trials, and the spread of scores is constrained by this ceiling, generating a negative skew.
