Improved clinical outcomes may be mediated by reduction in the extracellular fluid volume and improved blood pressure control, enhanced clearance of uremic toxins, or more consistent mineral metabolic control [ 11- 13].
Low-molecular-weight heparins (LMWHs) have several advantages over UFH, including a lower incidence of HIT, less affinity for antithrombin, less platelet (and polymorphonuclear cell) activation, less inactivation by platelet factor-4, greater and more consistent bioavailability, and no metabolic side effects [ 55].
This could be due to differences in the diet quality (C∶N ratio) of herbivorous relative to carnivorous species (the latter displaying much more consistent nitrogen discrimination [16]) and/or metabolic differences (such as herbivorous fish having greater excretion rates [16]).
28 The aerobic NMES exercise appears to have a metabolic profile more consistent with vigorous voluntary exercise an exercise intensity that many with type 2 diabetes may not engage in sufficiently.
Previous work (Ravasz et al., 2002) suggests that the metabolic network is more consistent with a fractal structure model, a mixture of a scale-free (Jeong et al., 2000) and modular network.
Importantly, there is also evidence that additive gene expression impacts heterosis by balancing expression of genes in metabolic pathways; for example a more consistent, and lower variation in metabolites has been reported for heterotic maize hybrids compared with their inbred parents, presumably caused by improved metabolic flux [ 41].
It is worth noting, as described above, that the evidence for the metabolic syndrome (an approximate index of insulin-resistance-related metabolic disturbance) as a risk factor for cancer is more consistent than for insulin alone.
Neuroinflammation has a deleterious effect and is therefore more consistent with the negative correlations we found in our patients between metabolic data and relevant cognitive scores.
Forager-upregulated genes showed a more consistent signal for underrepresented terms, for example, GO terms associated with metabolic processes and chromatin modification (Supplementary file 3).
In women and men, sitting time and TV viewing time were deleteriously associated with cardio-metabolic risk biomarkers, with sitting time having more consistent associations in both sexes and being independent of central adiposity.
