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For instance, the expression of FOXP3 seems to be a more consistent marker for functional Treg in mice, than it is in humans [26] [28].
Since the reliability of Helios to identify nTreg cells has been questioned 33, we also stained cells for neuropilin 1 (Nrp-1), which has recently been shown to be a more consistent marker of this subset 34, 35.
Syntenic depth provides a more consistent marker for large scale genomic events than changes in the copy number of individual genes which are influenced by a greater number of small scale processes (expansion and contraction of tandem arrays, transposon capture and duplication, etc).
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We have demonstrated that such pathway-based biomarkers (pathway features and leading edge gene markers) are significantly more consistent than single gene markers among different data sets.
Every shot will have roughly the same amount of air or CO2 behind it, thereby making the marker more consistent, accurate, and efficient.
Still, the more closely related populations such as VrnA, lpOA and pop8490 were more consistent in terms of the marker order between maps.
Instead, the high frequency of LOH for the natMX4 and hphMX4 markers is more consistent with transfer of the DSB from the CFV to the chromosome triggering secondary recombination events.
The nuclear markers provided more consistent estimates of cline width (30 and 32 km respectively) than the mitochondrial cyt-b gene (6 and 39 km), as expected from the lower sampling variance (nuclear markers also produced more variable and less consistent estimates when considered individually).
As shown there, the pathway/gene markers corresponding to a pathway-based analysis are more consistent than individual Fisher-selected gene markers selected directly from expression profiles.
In Potamotrygonidae, short and long repeats may also correspond to informative markers at the population level and may be used in combination with mitochondrial markers in a more consistent dual analysis.
This enabled us to know the linkage-phase between markers for a more consistent statistical analysis.
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