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Compared with non-squamous NSCLC, squamous NSCLC displays a more consistent immune profile, more frequently expresses specific tumor antigens and shows more extensive infiltration of CD8+ effector cells.
On the basis of these promising results, we would suggest that nicotine hapten clustering could provide a path forward to obtain more consistent immune responses across the population, something that has been strongly lacking in previous nicotine vaccines.
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For example, the category of neu cluster is more consistent over the broader category of immune system evasins.
There is also a study showed that the anti-CD25 mAb selectively depleted cells with highest level of CD25 expression, and the changed intensity of immune response was more consistent with the depletion of Treg cells than that of effector T cells [37].
The reported effects of NUC treatment on adaptive immune cells are more consistent, because an increased frequency and function of HBV-specific CD4 and CD8 T cells is reported in multiple studies.
A possible explanation for this may be that HPV 51, although highly prevalent, is cleared more quickly and possibly causes a more consistent immunologic response with a longer immune protection conferred to those that have cleared the virus, making them no longer susceptible to new infections.
Humans' immune cell counts, the authors note, are more consistent with those of monogamous primates than promiscuous ones.
"More consistent now".
"It's more consistent.
"A little more consistent.
Appetizers seem more consistent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com