Sentence examples for more conserved regions from inspiring English sources

We also designed our primers to match more conserved regions of HIV.

During acute infection, immune responses to Nef are typically replaced by responses to more conserved regions of HIV-1 [42].

Clustering of epitopes was evident, with the majority of epitopes found in the more conserved regions of HIV-1 Env (Fig. 1a), as has been described previously[21].

Importantly, DNA vaccines have afforded significant protection against heterologous challenges with genetically drifted strains (e.g., heterosubtypic immunity) in animal models, an outcome that may be due to their ability to also induce robust CD8+ cytotoxic T lymphocyte (CTL) responses against more conserved regions of the virus [1], [2], [3], [4], [5].

Thus, the most variable regions of TR (CDR3) are positioned in the center of binding interface where they contact the peptide, whereas the more conserved regions of TR (CDR1 and CDR2) and the tops of MHC helices engage in contacts that surround the central CDR3-peptide region like a "gasket" [4].

Future studies independent of alignments should detect even more conserved regions.

Since the current study was limited to oocytes, however, we do not yet know if the sequences active for expression are also responsible for somatic silencing, or if silencing might be due to a separate, more conserved region of the promoter.

For that reason, the length of our GI specific TaqMan probe could be optimized to fit to a shorter, more conserved region of all GI genotypes known.

In addition, the second part of the ndhF gene was sequenced as it has been shown to be more variable than the more conserved 5' region and is thus more appropriate for species-level analyses [ 32].

Forward 3 was designed on the Q6A1C9 sequence, targeting the more conserved region before the start codon between sequences Q6A1C9 and Q6A1D7 obtained from Onobrychis viciifolia and Astragalus monspessulanus.

Therefore, the increased signal reported from the longer elements may be due to an increasing proportion of cross-hybridisation with other members of the actin superfamily, which will bind to the more conserved region of the element DNA.