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The most unusual feature of CMITEs is conservation of the internal region, which is more conserved between MITE families than the TIRs.
However, in comparison to other MITEs of the same origin [30] [32], CMITEs have the following noteworthy features: The most unusual feature of CMITEs is conservation of the internal region, which is more conserved between MITE families than the TIRs.
The three dimensional structures of OppA proteins are likely more conserved between different species than their primary amino acid sequences.
Third, NR activation by environmental chemicals may be more conserved between rodents and humans than previously believed [42].
Conversely, PK genes preferentially expressed in nervous tissue are more conserved between the human and mouse in the coding regions and UTRs, indicating elevated selection pressure on amino acid sequences and on RNA regulatory sequences.
Bearing that in mind, we intended to define the consensus differences in KEGG pathways which are more conserved between colonic epithelial cells and mucosa than between normal and neoplastic tissues.
Despite this inter-serotype variability, the P1-P2 sequence of 5'NCR was significantly more conserved between clinical isolates and the corresponding reference prototype strain (mean divergence 3.5%) compared to the NIm-1A coding sequences of VP1 (mean divergence 9.6%, Table 1).
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It is expected that HCE genomic location should be more conserved for the comparison between human and rodent than between human and non-mammalian species due to the relatively shorter evolutionary distance.
For positions that are much more conserved, the joint probability between them and other less conserved positions is approximately equal to the product of the individual probabilities of the latter position, resulting in low MI (see Equation 1 in Methods).
The orthologs that are involved in CCNs have been shown to be more conserved in gene expression between species [27], which should be a better reference set for cross-species comparison of gene expression than WOS.
Ultraconserved elements (UCEs) were originally defined as regions of 200 bp or more conserved at 100% identity between human and rodent genomes [ 19].
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