From a methodological viewpoint this is not a concern as an overestimate of allelic dropout can only lead to more conservative protocols, ensuring higher data fidelity.
Overall, this scenario represents an additional reason for shifting to HPV testing but will require even more conservative protocols, to achieve high PPV for colposcopy referral, both in order to avoid false positive histological diagnoses (that are inversely related to the PPV of referral [ 23]) and to maintain sustainable overall costs of cervical cancer control.
Thus, it remains to be determined to what extent similarly accurate assays of myeloarchitecture can be derived using more conservative spherical acquisition protocols as often employed on clinical 1.5T and 3.0T scanners for in vivo applications.
In 20 cases (21%) of patients, the physicians recommended more conservative measures than the protocol.
More conservative return-to-play protocols with a greater focus on active rehabilitation of the systems likely impacted by a concussive injury may prove helpful – this study was not designed to answer this question".
In addition, it has been thought that house staff in public institutions may be held more strictly to conservative protocols than the private physicians.
Thus in order to control for variance at baseline, ANCOVA was used with baseline Time 1 scores covarying for the dependent outcome scores and a more conservative ITT analysis selected over per protocol analysis.
Although this trial utilized a more conservative and better-tolerated dose titration protocol than FREEDOM-C or FREEDOM-M, it failed to meet the primary end point, with a +10 m placebo-corrected Hodges Lehmann between-treatment median difference in 6MWD at 16 weeks (P=0.089).
Thus, without moment limit definition for the hybrid protocol, using a torque-control protocol may be safer and more conservative for long fusion constructs.
This certainly applies to our suggestions for modifying the CBCL and CPRS-R L protoCPRS-R L using more conservative cutoffs than those protocolsby the mandals when assessing children with SLI and other developmental langusingdisorders.
