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We also did all analyses with a more conservative data set in which polymorphisms called in only a single line were removed (table 1, nonsingletons).
We have tried to make up for this deficiency by multiple imputation, establishing a comparison with original data and showing more conservative data.
These patients were excluded from our data analysis, and our more conservative data analysis method might have overestimated the death probability.
If we included those non-mating pairs (substituted a value of 90 min for mating latency – the maximum duration of observation), we found, for the most part, the same results as in our more conservative data set.
Although we are confident that most of the observed SCPs are not sequencing or assembly errors, we created a more conservative data set by removing alleles that were present only once across the two D. melanogaster populations (table 1, nonsingletons).
Full molecular replacement and refinement of the data to 2.7 Å, using a more conservative data cut-off (I/σI=2), showed that the electron density did not change, but automatic rebuilding failed, indicating that the weak data contained significant information and that any errors in their measurement were sufficiently reduced by the use of maximum likelyhood refinement.
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In a more conservative test, data for all parents from both families were combined and assessed with single marker analysis for each trait independently.
The molecular data were more reliable and more conservative than morphological data.
As a result, detailed analyses provided more realistic and conservative data than those in the ANSI/ANS 58.2 standard used in the current HELB design while the jet loads did not threat secondary structural integrity after the MSL piping break.
The company puts that one-week battery life down to its use of narrowband network technology — a standard that optimizes power usage through more conservative use of data — and it claims its tags are the first of their kind to utilize it.
This suggests that these relationships were adequately captured by natural cubic splines, which were chosen for the main model because of their more conservative smoothing of data and the gain of a degree of freedom.
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