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Blood viraemia results were reported previously [ 4] and are indicated in Table 2 as positive if total CSFV viral RNA could be detected in blood from an animal on two or more consecutive sampling days.
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If any of the 3 specimens were culture positive then samples were collected in clinic until two or more consecutive samples were TB culture negative.
Among 911 children, 27 developed positivity for two or more islet autoantibodies in two or more consecutive samples (case subjects).
Non-genotype specific persistence includes all cases with two (or more) consecutive samples positive for different HPV genotypes.
An episode of pneumococcal carriage was defined as isolation of pneumococcus from 1 or more consecutive samples.
The end point for this study, islet autoimmunity, was defined as positivity for two or more islet autoantibodies in two or more consecutive samples.
Luteal activity was defined as the presence of progesterone concentrations >1.6 nmol/L (0.5 ng/ml) in three or more consecutive samples.
Of these, 60 women had one or more consecutive samples immediately following smoking initiation when they also tested negative for HPV DNA and were cytologically normal.
Subclinical breakthrough HBV infection was defined as one or more HBV markers positive in one or more consecutive samples, excluding conditions for chronic HBV infection and false-positive result, without any reported clinical symptoms of hepatitis.
Samples obtained in the first 72 hours of ICU admission were discarded since positive samples obtained on admission were not an indication to start amphotericin B. Colonization was defined as the presence of Candida in two or more consecutive samples obtained on different days.
Patients in whom Staphylococcus (non- S. aureus) was isolated from blood cultures were not eligible, except if two or more consecutive samples grew the same species harboring the same antibiotic resistance pattern [ 10]. cVariable defined as patients who developed a new and persistent radiographic infiltrate.
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