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However, as new functional understandings are revealed, and as KIR population genetics is more comprehensively defined and genotyping becomes more extensive, refined, and economical, we can fully expect to achieve this long sought goal.
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So, while it has been proposed many times that evolution has likely exploited their overlapping specificities and potential complexity to regulate classes of cargoes by regulating the karyopherins, it remains for the field to more comprehensively define Kap-cargo complexes to demonstrate how much this is the case and to fully appreciate how they may have done so.
These reference genes have not been comprehensively defined to date.
However, the different behaviours that contribute to this process have not been comprehensively defined.
This study comprehensively defines the clinical association between intestinal permeability increases and nonalcoholic steatohepatitis.
Wisneski et al. [ 116] utilized ECoG recordings to comprehensively define ipsilateral physiology in motor-intact patients undergoing invasive monitoring.
These markers do, however, comprehensively define an algorithm that significantly segregates BLBCs versus other breast cancer entities.
The ANRQ has fulfilled the requirements of this analysis more comprehensively than any other instrument examined based on the defined rating criteria.
All assessment tools received an overall rating of not recommended; however, the ANRQ has fulfilled the requirements of this analysis more comprehensively than any other instrument examined here based on the defined rating criteria.
It is clear that the better we define the gene sequences, the better and the more comprehensively we will be able to do good research in this highly attractive model system.
Third, as new genomic data continue to be generated for these distant species, our work could be extended with a method that more comprehensively characterizes gene family relationships beyond orthology, such as the methods used for the EnsemblCompara GeneTrees [ 50] or other methods that define gene age according to more dynamic properties [ 51].
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