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OCSCs were more comprehensively characterized by the combination of CD133 and the stem cells marker aldehyde dehydrogenase (ALDH) [ 24, 25].
Peptide toxins from Conus geographus venom have been more comprehensively characterized than for any other venom, but the transcriptomic analysis reported above provides significant new insights into the mechanism of prey capture by the snail.
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Thus, to more comprehensively characterize the melanoma miRNAome, assessment of a large number of melanomas at different stages of progression is needed.
To overcome the limitations associated with microarray studies, we used "next generation" sequencing technology (specifically massively parallel pyrosequencing using the 454 Life Sciences platform) of small RNA cDNA libraries to more comprehensively characterize miRNA expression in epithelial ovarian cancer, as well as in primary cultures of normal ovarian surface epithelial cells.
Lastly, the addition of ecological data would complement the results from this genetic study for more comprehensively characterizing mating systems in these Neotropical waterbirds.
Our aim was to map the distribution of MAT/MATX genes within the Euglenida in order to more comprehensively characterize the evolutionary history of MATX.
More comprehensive analysis of circulating androgens and maternal smoking effects in the human male fetus would therefore be required in order to more comprehensively characterize the impact of smoking on steroidogenesis.
Third, as new genomic data continue to be generated for these distant species, our work could be extended with a method that more comprehensively characterizes gene family relationships beyond orthology, such as the methods used for the EnsemblCompara GeneTrees [ 50] or other methods that define gene age according to more dynamic properties [ 51].
Of the 104 tumors that we comprehensively characterized, 50%% (52 out of 104 cases) displayed mutations in two or more SMGs, 44%% (46 out of 104 cases) of cases harbored alterations in one SMG, and six cases did not have mutations in any of the SMGs.
Monitoring gene expression is experimentally more tractable than comprehensively characterizing glycan structures associated with each model system, and we therefore chose this route for an initial investigation.
The catalysts are comprehensively characterized through TEM, XRD and XPS.
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