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Three different materials (superalloys IN-939, Rene80, steel 26NiCrMoV14-5) and three different geometry types (smooth, notch, cooling hole specimens) are considered for a more comprehensive validation of the probabilistic LCF model and to demonstrate its wide application range.
For a more comprehensive validation, other five cases (see Figure 10) are analyzed both analytically and through simulation, and the results are presented in Table 4.
As GIS approaches continue to expand and improve, a more comprehensive validation procedure may be performed with a network of experts, facilitated through an online portal.
More comprehensive validation measures should be developed in near future.
Consequently, system qualification rather than the more comprehensive validation is generally performed for modeling software.
The lines sequenced in this study were chosen to represent the diversity within the more comprehensive validation panel.
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Undoubtedly, the need to bridge the gap between promising preclinical trials and effective translational bedside treatment prompts further investigations towards mapping out the mechanistic pathways of MCD, understanding how these drugs work as medicine in the body and more comprehensive target validations.
Study methods that collect and incorporate more comprehensive confounder data on a validation cohort may reduce confounding bias.
In order to comprehensively investigate whether certain rare CNVs [e.g. large (>1 Mb) CNVs (cf. 22)] predispose to obesity, a more comprehensive quality control (QC) and validation of each single CNV call as well as a much larger adequately powered analysis sample is needed.
Mindful of minimising patient sample volume, the Searchlight Multiplex ELISA system was also included (Aushon BioSystems, Boston, MA, USA) allowing further validation and a more comprehensive evaluation of sample stability.
As an alternative, limitations of the current grammar induction process could be complemented by selecting the best grammar classifier from several trained candidates by means of validation, especially if more comprehensive datasets are available.
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more in depth validation
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