Sentence examples for more comprehensive mutation from inspiring English sources

A new selection operator and a more comprehensive mutation operator are used.

Next-generation DNA sequencing provides an opportunity to provide carrier screening using more comprehensive mutation panels that are limited primarily by information about the clinical impact of detected sequence changes.

Recently, next-generation sequencing has been put to practical use and has allowed a more comprehensive mutation analysis with potential savings of time and money.

Recent technological advances in DNA sequencing have yielded more comprehensive identification of mutations occurring in tumors.

To generate a more comprehensive picture of the mutation spectra arising in MMR-deficient tumors, and in particular, to interpret their clinical relevance with respect to diagnostically assessing MSI and therapeutically targeting MMR-deficient tumors, we sequenced another comprehensive set of MMR-deficient tumors.

To provide a more comprehensive screen for possible mutations causing the hypercholesterolemia in the child, whole-genome sequencing was performed by Complete Genomics, Inc. (Mountain View, CA, USA), using a sequencing-by-ligation method as described in detail previously (19).

Given the rate of increase and the ability of double-mutant allele lineages to acquire the super resistance conferring A581G mutation independently, it is vital for the continuing effectiveness of prophylaxis with SP that more comprehensive surveillance for the A581G mutation be used to track emerging super-resistant malaria in Africa.

The signature is, therefore, more comprehensive and predictive than the mutation status alone.

So about five years ago, Meyerson and Levi Garraway, an oncologist and scientist at Dana-Farber, set out to create a more comprehensive test for cancer-linked mutations.

We sought to develop a next-generation DNA sequencing based workflow to enable analysis of a more comprehensive set of disease-causing mutations.

Ultimately, more realistic biological models of tumor development and a more comprehensive understanding of the relationship between individual mutations will be necessary to classify mutations according to their role in the underlying process of tumor progression (reviewed in [ 75]).