Sentence examples for more comprehensive dna from inspiring English sources

The recent availability of array-based techniques offers the opportunity for a more comprehensive DNA methylation profiling [ 11, 12].

More comprehensive DNA sequencing approaches, such as the use of next-generation technologies for whole-exome or whole-genome resequencing, may enable the identification of the causative mutation of Rottweiler LEM.

Note that yeast cell assay incorporated much more key biomarkers of DNA damage repair pathways than the human cell assay and therefore captures more comprehensive DNA damage information, which may explain the better correlation of comet assay results with yeast cells than with human cells.

Alternative techniques such as sequencing of immunoprecipitated methylated DNA (MeDIP-seq) or of bisulfite-treated genomic DNA (BS-seq) provide a more comprehensive picture of DNA methylome [ 23] but, despite the recent introduction of pipelines for their automatization and analysis [ 24– 27], are still more laborious and expensive.

The aim was to generate a more comprehensive image of DNA degradation in SLE and determine what sources of DNA most likely are involved in disease pathology.

An even more comprehensive picture of DNA looping will emerge once a more complete understanding of the kinetics of loop formation is attained [20], [55], [65].

More recently, high-throughput, genome-wide quantitative methylation platforms have become available, allowing a more comprehensive overview of DNA methylation (Bibikova et al, 2006; Bibikova and Fan, 2009).

Finally, we synthesized our results with those from other recent investigations to advance a more comprehensive understanding of DNA methylation in insects.

In addition, developments in mass spectrometry are permitting, for example, the more comprehensive analysis of DNA adducts as biomarkers of exposure [ 7].

Despite being much more comprehensive, sequencing-based DNA methylome technologies are still cost inhibitory for directly profiling the large cohort of specimens that is often required to obtain power to detect most epigenetic events significantly associated with cancer.

Therefore, even if we should be careful about sequence mismatches within and between species, the information from both macaque transcripts and the rhesus genome can be combined to build more versatile and comprehensive DNA microarrays that can be used for biomedical surveys using laboratory macaques.