Your English writing platform
Discover LudwigExact(1)
After initial fixes that allowed the core metabolites to be produced, we incrementally added more compounds to the biomass.
Similar(59)
We attribute this to the fact that the levels of E6 and p53 are higher in our cell-free system, thereby requiring more compound to achieve the same effect.
In continuation of our goal to rationally develop effective small molecule azomethines against Hsp90, we designed few more compounds belonging to the class of 2,4-dihydroxy benzaldehyde derived imines (1 13) with our validated docking protocol.
To dissect the physio-pathological pathways in which QR2, MT3 and melatonin meet, one needs more compounds binding to MT3 and/or inhibitors of QR2 enzymatic activity.
It decreases the solubility of compounds in the liquid phase, which results in more compounds moving to the gas phase.
The registration of compounds becomes even more complicated when two or more compounds have to be registered together as a mixture that has a particular mixture-specific property.
This indicated that, from a toxicological perspective, more compounds needed to be considered.
Our results suggest that the inhibitors of cAMP-selective PDEs may be more effective than the inhibitors of cGMP-selective PDEs (although more compounds need to be tested), indicating the importance of the intracellular cAMP level in cardiac reprogramming.
Screening of >300 000 more compounds led to the identification of hits 49– 51 with long flexible aliphatic linkers connecting the Fe-coordinating imidazole moiety with a second aromatic functionality, as well as a ring-constrained analogue 52.
Adding more predictive compounds to the model generates more accurate models.
While SAscore model tends to predict more compounds as easy-to-synthesize, DR model labels a majority of compounds as hard-to-synthesize.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com