In principle, this methodological framework can readily accommodate more complicated disease dynamics such as immigration, latent infected states, missing data, and vector-communicated diseases, as well as more complicated intervention strategies that allow combined vaccination and quarantine.
Point-of-use water treatment has proven to be a more complicated intervention; powdered chlorine to add to water and charcoal for boiling water are expensive, and water purification tablets are donor driven and lack standardization across organizations.
Simple interventions such as reminders were found to be efficacious at improving attendance, and more complicated and costly interventions were not more efficacious.
It is important to remember that children's asthma disproportionately affects low-income urban households (IOM 2000) in which parents may find it difficult to achieve some of the more costly or complicated interventions described in the studies above.
DTA meta-analyses have different characteristics making assessment of the potential for publication bias more complicated than for intervention reviews.
However, endogenous release of these neurotransmitters in the bladder is likely to be more complicated than the experimental interventions.
Better they realize that as toddlers than as teens, when interventions become more complicated, she adds.
The other model predicted rapid declines in the level of resistance when use is reduced, and a more complicated relationship between the effectiveness of interventions and the level of transmission within the hospital (59 ).
Reactions by this mechanism can be complicated by the intervention of intermediates that are more complicated structurally.
Analysis will include elementary head-to-head comparisons of the intervention groups as well as more complicated multi-level analysis incorporating patients and time measurements if necessary.
