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We chose to use a stepwise Bonferroni-type procedure for multiple testing since simulation studies have confirmed that such procedures generally perform as well or better than more complicated alternative procedures (Cribbie, 2017).
As it will be commented on in detail later in this letter, we have observed that both Equation 4 and the more complicated alternative are able to predict essentially the same filtering performances and time evolutions, and so in the following, we will employ the simpler Equation 4 unless stated otherwise.
For more complicated alternative hypotheses, P-values can be obtained easily by simulation under the null.
The rest of the genes (n = 964) showed more complicated alternative splicing events and it was not possible to classify the events into these simple six categories.
We did not perform joint optimizations with NOx and PM, which could be used to examine more complicated alternative study designs such as census block groups with low reduction levels in NOx but intermediate to high reductions in PM.
Accordingly, in this revision, we have added a slightly more complicated alternative model in which Cdr2 is modified on the membrane, and then may diffuse through the cytoplasm to arrive at the nodes.
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Only then will we be in a position to evaluate the more complicated alternatives developed by actualists in the attempt to avoid commitment to nonactual possibles.
Suppose the more complicated and demanding alternative Code B would have an expected value of \(n + 5\) once Code B has been accepted.
In Section 4, two alternative, more complicated distributed network scenarios are postulated.
The interactive network among these genes in colorectal cancers became more complicated due to frequent alternative splicing.
Standalone tools for proteasomal cleavage and TAP transport did not reach as widespread acceptance as MHC prediction tools, because these events are more complicated to model and alternative pathways also interfere.
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